Mitochondrial Dysfunction in Depression

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چکیده

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Mitochondrial Dysfunction in Depression

BACKGROUND Depression is the most debilitating neuropsychiatric disorder with significant impact on socio-occupational and well being of individual. The exact pathophysiology of depression is still enigmatic though various theories have been put forwarded. There are evidences showing that mitochondrial dysfunction in various brain regions is associated with depression. Recent findings have spar...

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Cognitive Dysfunction in Depression

Cognitive Dysfunction' was assessed in 30patients diagnosed to have Major Depression (DSM III R), using the PCI memory scale and the Wechsler Adult Performance Intelligence Scale, form PR both of which have been developed and standardised in India. Depressed patients revealed marked impairment on tests of attention and concentration, and immediate and delayed recall on tests of memory (PCI); wh...

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Cognitive Dysfunction in Depression

Thirty patients of primary depression were assessed for their cognitive functions initially in the depressed state and on complete recovery. The results indicate presence of definite cognitive impairment during the depressed state (as measured by the Bhatia's Battery test and PGI memory scale) which is restored to normal after recovery from depression. The intensity of depression as indicated b...

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ژورنال

عنوان ژورنال: Current Neuropharmacology

سال: 2016

ISSN: 1570-159X

DOI: 10.2174/1570159x14666160229114755